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Article

Systematic expression analysis of ligand-receptor pairs reveals important cell-to-cell interactions inside glioma

22 May 2019

Abstract excerpt

BACKGROUND: Glioma is the most commonly diagnosed malignant and aggressive brain cancer in adults. Traditional researches mainly explored the expression profile of glioma at cell-population level, but ignored the heterogeneity and interactions of among glioma cells. METHODS: Here, we firstly analyzed the single-cell RNA-seq (scRNA-seq) data of 6341 glioma cells using manifold learning and identified neoplastic...

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Share to Glioma Diagnosis and Treatment
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PMID: 31118022
DOI: 10.1186/s12964-019-0363-1

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