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The clinicians´ dilemma with mosaicism—an insight from inner cell mass biopsies

9 Apr 2019

Abstract excerpt

STUDY QUESTION: How reliable are cleavage stage and trophectoderm (TE) biopsies compared to inner cell mass (ICM) biopsies? SUMMARY ANSWER: The reliability of TE biopsy compared to ICM biopsy is almost perfect, but only substantial between cleavage stage biopsy and ICM biopsy. WHAT IS KNOWN ALREADY: One of the prevailing reasons for implantation failure is presumed to be chromosomal aneuploidy in human...

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PMID: 31114858
DOI: 10.1093/humrep/dez055

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