Article
Detection of mosaicism at blastocyst stage with the use of high-resolution next-generation sequencing
6 Apr 2017
Abstract excerpt
A significant proportion of human preimplantation embryos produced during the course of in vitro fertilization (IVF) treatments contain two or more cytogenetically distinct cell lines. This phenomenon, known as chromosomal mosaicism, can involve the presence of cells with different types of aneuploidy in the absence of any normal cells or a mixture of euploid and abnormal cells. Although a high prevalence of...
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