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Tissue-specific knockout of E-cadherin ( Cdh1 ) in developing mouse gonads causes germ cells loss

16 May 2019

Abstract excerpt

The normal course of gonad development is critical for the sexual development and reproductive capacity of the individual. During development, an incipient bipotential gonad which consists of unorganized aggregate of cells, must differentiate into highly structured testis or ovary. Cell adhesion molecules (CAMs) are a group of proteins crucial for segregation and aggregation of different cell types to form...

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PMID: 31100714
DOI: 10.1530/rep-18-0621

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