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Classical cadherins in the testis: how are they regulated?

17 Sept 2023

Abstract excerpt

Cadherins (CDH) are crucial intercellular adhesion molecules, contributing to morphogenesis and creating tissue barriers by regulating cells' movement, clustering and differentiation. In the testis, classical cadherins such as CDH1, CDH2 and CDH3 are critical to gonadogenesis by promoting the migration and the subsequent clustering of primordial germ cells with somatic cells. While CDH2 is present in both Sertoli...

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PMID: 37717581
DOI: 10.1071/rd23084

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