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Article

Specific deletion of Cdh2 in Sertoli cells leads to altered meiotic progression and subfertility of mice.

Biology of reproduction - 1 Mar 2015

Jiang Xiaohua, Ma Tieliang, Zhang Yuanwei, Zhang Huan, Yin Shi, Zheng Wei, Wang Liu, Wang Zheng, Khan Manan, Sheikh Salma W, Bukhari Ihtisham, Iqbal Furhan, Cooke Howard J, Shi Qinghua

Abstract excerpt

CDH2 (cadherin 2, Neural-cadherin, or N-cadherin) is the predominant protein of testicular basal ectoplasmic specializations (basal ES; a testis-specific type of adhesion junction), one of the major cell junctions composing the blood-testis barrier (BTB). The BTB is found between adjacent Sertoli cells in seminiferous tubules, which divides the tubules into basal and adluminal compartments and prevents the...

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Identifiers

PMID: 25631347
DOI: 10.1095/biolreprod.114.126334

Genes

CDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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