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Hydro-Seq enables contamination-free high-throughput single-cell RNA-sequencing for circulating tumor cells

15 May 2019

Abstract excerpt

Molecular analysis of circulating tumor cells (CTCs) at single-cell resolution offers great promise for cancer diagnostics and therapeutics from simple liquid biopsy. Recent development of massively parallel single-cell RNA-sequencing (scRNA-seq) provides a powerful method to resolve the cellular heterogeneity from gene expression and pathway regulation analysis. However, the scarcity of CTCs and the massive...

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PMID: 31092822
DOI: 10.1038/s41467-019-10122-2

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