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Article

Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas.

Journal of the National Cancer Institute - 1 Jan 2020

Gallardo Miguel, Malaney Prerna, Aitken Marisa J L, Zhang Xiaorui, Link Todd M, Shah Vrutant, Alybayev Sanzhar, Wu Meng-Han, Pageon Laura R, Ma Huaxian, Jacamo Rodrigo, Yu Li, Xu-Monette Zijun Y, Steinman Haley, Lee Hun Ju, Sarbassov Dos, Rapado Inmaculada, Barton Michelle C, Martinez-Lopez Joaquin, Bueso-Ramos Carlos, Young Ken H, Post Sean M

Abstract excerpt

BACKGROUND: Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is an RNA-binding protein that is aberrantly expressed in cancers. We and others have previously shown that reduced hnRNP K expression downmodulates tumor-suppressive programs. However, overexpression of hnRNP K is the more commonly observed clinical phenomenon, yet its functional consequences and clinical significance remain unknown. METHODS:...

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Share to Antineoplastic Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Lymphoma, B-Cell

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Share to Protein Interaction Domains and Motifs

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Identifiers

PMID: 31077320
DOI: 10.1093/jnci/djz078
PMCID: PMC7489062

Genes

MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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