Article
Host heterogeneous ribonucleoprotein K (hnRNP K) as a potential target to suppress hepatitis B virus replication.
PLoS medicine - 1 Jul 2005
Ng Lisa F P, Chan Marieta, Chan Soh-Ha, Cheng Paul Chung-Pui, Leung Eastwood Hon-Chiu, Chen Wei-Ning, Ren Ee-Chee
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) infection results in complications such as cirrhosis and hepatocellular carcinoma. Suppressing viral replication in chronic HBV carriers is an effective approach to controlling disease progression. Although antiviral compounds are available, we aimed to identify host factors that have a significant effect on viral replication efficiency. METHODS AND FINDINGS: We studied a group...
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