Article
Increased expression of the heterogeneous nuclear ribonucleoprotein K in pancreatic cancer and its association with the mutant p53.
International journal of cancer - 15 Jan 2010
Zhou Renyuan, Shanas Reneé, Nelson Mark A, Bhattacharyya Achyut, Shi Jiaqi
Abstract excerpt
The heterogeneous nuclear ribonucleoprotein (hnRNP) K is an essential RNA and DNA binding protein involved in gene expression and signal transduction including DNA transcription, RNA splicing, RNA stability and translation. The role of hnRNP K in cancer is relatively understudied. However, several cellular functions strongly indicate that hnRNP K is involved in tumorigenesis. In this study, we investigated the...
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