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Article

Targeting the signalling pathways regulated by deubiquitinases for prostate cancer therapeutics

6 May 2019

Abstract excerpt

Prostate cancer (PCa) is the most common cancer diagnosed and the second most common cause of cancer-related death in men worldwide. The current androgen deprivation therapy for PCa cannot fully cure this disease. Moreover, androgen receptor gene amplification and mutation are associated with PCa to develop castration-resistant prostate cancer (CRPC). This review focuses on the deubiquitinases (DUBs) involved in...

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PMID: 31062387
DOI: 10.1002/cbf.3401

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