Article
Cardiovascular disease contributes to Alzheimer's disease: evidence from large-scale genome-wide association studies.
Neurobiology of aging - 1 Apr 2014
Liu Guiyou, Yao Lifen, Liu Jiafeng, Jiang Yongshuai, Ma Guoda, Chen Zugen, Zhao Bin, Li Keshen
Abstract excerpt
Alzheimer's disease (AD) is the most common and complex neurodegenerative disease in the elderly individuals. Recently, genome-wide association studies (GWAS) have been used to investigate AD pathogenesis. These GWAS have yielded important new insights into the genetic mechanisms of AD. However, these newly identified AD susceptibility loci exert only very small risk effects and cannot fully explain the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
