High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach

Abstract excerpt

Lifelong infection of the gastric mucosa by Helicobacter pylori can lead to peptic ulcers and gastric cancer. However, how the bacteria maintain chronic colonization in the face of constant mucus and epithelial cell turnover in the stomach is unclear. Here, we present a new model of how H. pylori establish and persist in stomach, which involves the colonization of a specialized microenvironment, or microniche,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Helicobacter pylori-related gastroenterology studies
• Share to Mycobacterium research and diagnosis
• Share to Veterinary medicine and infectious diseases