Article
Nanofiber-hydrogel composite-mediated angiogenesis for soft tissue reconstruction.
Science translational medicine - 1 May 2019
Li Xiaowei, Cho Brian, Martin Russell, Seu Michelle, Zhang Chi, Zhou Zhengbing, Choi Ji Suk, Jiang Xuesong, Chen Long, Walia Gurjot, Yan Jerry, Callanan Megan, Liu Huanhuan, Colbert Kevin, Morrissette-McAlmon Justin, Grayson Warren, Reddy Sashank, Sacks Justin M, Mao Hai-Quan
Abstract excerpt
Soft tissue losses from tumor removal, trauma, aging, and congenital malformation affect millions of people each year. Existing options for soft tissue restoration have several drawbacks: Surgical options such as the use of autologous tissue flaps lead to donor site defects, prosthetic implants are prone to foreign body response leading to fibrosis, and fat grafting and dermal fillers are limited to small-volume...
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