Article

Biomaterial scaffold-based gene delivery for the repair of complex wounds: Challenges, progress, and future perspectives

2025-04-24

Abstract excerpt

Biomaterial scaffolds play a crucial role in enhancing wound repair by offering structural support, promoting cell proliferation, and tissue formation. When combined with gene therapy, these scaffolds may become powerful tools for wound healing, enabling the localized delivery of therapeutic genes that stimulate tissue regeneration. While in a nascent stage of translation, gene-activated scaffolds may hold conside...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 42cf96f6-3802-5cdf-9116-43a75ea7e713
DOI: 10.1016/j.celbio.2025.100073

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Biomaterial scaffold-based gene delivery for the repair of complex wounds: Challenges, progress, and future perspectivesDOI 10.1016/j.celbio.2025.100073Read

Biomaterial Scaffolds for Controlled, Localized Gene Delivery of Regenerative FactorsSemantic proximity Read

Exploring the evolution of tissue engineering strategies over the past decade: From cell-based strategies to gene-activated matrixSemantic proximity Read

Three‐dimensional porous scaffolds at the crossroads of tissue engineering and cell‐based gene therapySemantic proximity Read

Human-Derived Scaffold Components and Stem Cells Creating Immunocompatible Dermal Tissue Ensuing Regulated Nonfibrotic Cellular Phenotypes.Semantic proximity Read

Novel Hydrogels for Drug Delivery and Regenerative Medicine: Advances, Engineering Strategies, and Clinical TranslationSemantic proximity Read

Emerging technologies in regenerative medicine: The future of wound care and therapySemantic proximity Read

Biomaterial‐based gene therapySemantic proximity Read

Fabrication of biocompatible artificial skin for full-thickness wound by co-culture of adipose mesenchymal stem cells-human keratinocytes on oxygen-producing nanofiber electrospun scaffold in rat animal modelSemantic proximity Read

Nanofiber-hydrogel composite-mediated angiogenesis for soft tissue reconstruction.Semantic proximity Read

An SDF-1α gene-activated collagen scaffold restores pro-angiogenic wound healing features in human diabetic adipose-derived stem cellsSemantic proximity Read

Generation of a novel human dermal substitute functionalized with antibiotic-loaded nanostructured lipid carriers (NLCs) with antimicrobial properties for tissue engineeringSemantic proximity Read

Growth factors and growth factor gene therapies for treating chronic woundsSemantic proximity Read