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Functional high capacity exosome-encapsulating bioinspired hydrogel promotes microvascular bed expansion in diabetic mice

2024-08-26

Abstract excerpt

Chronic wounds present a significant clinical challenge due to impaired skin microvasculature, particularly in diabetes. The tissue engineering study introduces therapeutic Exo-Q, a unique thermoresponsive polymer hydrogel created with Q protein nanofibers and cultured human bone marrow multipotent stromal cell exosomes with consistent gene signature. Limited, local and topical application of Exo-Q hydrogel is fea...

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Identifiers and source

Literature Corpus work
6f821a40-84a2-583b-8b96-67573f48ad30
DOI
10.1101/2024.08.23.609402
Open publication

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Functional high capacity exosome-encapsulating bioinspired hydrogel promotes microvascular bed expansion in diabetic miceDOI 10.1101/2024.08.23.609402
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