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Article

Modulation of ADAR mRNA expression in patients with congenital heart defects

30 Apr 2019

Abstract excerpt

Adenosine (A) to inosine (I) RNA editing is a hydrolytic deamination reaction catalyzed by the adenosine deaminase (ADAR) enzyme acting on double-stranded RNA. This posttranscriptional process diversifies a plethora of transcripts, including coding and noncoding RNAs. Interestingly, few studies have been carried out to determine the role of RNA editing in vascular disease. The aim of this study was to determine...

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PMID: 31039163
DOI: 10.1371/journal.pone.0200968

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