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Multiparameter flow cytometry applications in the diagnosis of mixed phenotype acute leukemia

29 Apr 2019

Abstract excerpt

Mixed phenotype acute leukemias (MPALs) represent a rare subgroup of acute leukemias with a poor prognosis. Proper diagnosis and classification of MPAL is extremely important for patients' outcome. Morphology and flow cytometry recognize two types of MPAL: the "bilineal" MPAL with the coexistence of two blast populations of different lineage and truly "biphenotypic" MPAL coexpressing markers of more than one...

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PMID: 31033213
DOI: 10.1002/cyto.b.21783

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