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Article

STAT3 Post-Translational Modifications Drive Cellular Signaling Pathways in Prostate Cancer Cells

12 Apr 2019

Abstract excerpt

STAT3 is an oncoprotein overexpressed in different types of tumors, including prostate cancer (PCa), and its activity is modulated by a variety of post-translational modifications (PTMs). Prostate cancer represents the most common cancer diagnosed in men, and each phase of tumor progression displays specific cellular conditions: inflammation is predominant in tumor's early stage, whereas oxidative stress is...

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PMID: 31013746
DOI: 10.3390/ijms20081815

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