Article

SENP3 Promotes Bladder Cancer Proliferation and EMT Transformation by Affecting the Expression of PYCR1 via DeSUMOylation of STAT3

2021-09-17

Abstract excerpt

<title>Abstract</title> <p>Abnormal activation of signal transducer and activator of transcription 3 (STAT3) has been found in various types of human cancers, including bladder cancer (BC). In our study, we examined the regulation of STAT3 post-translational modifications (PTMs) and found that SENP3 is high in bladder cancer. SENP3 and STAT3 were highly expressed in BC tissues when compared with tissue adjacent t...

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Literature Corpus work: 67fcff7e-b33e-574a-b435-5c4939115e90
DOI: 10.21203/rs.3.rs-875422/v1

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