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Arsenic, Stem Cells, and the Developmental Basis of Adult Cancer

11 Nov 2010

Abstract excerpt

That chemical insults or nutritive changes during in utero and/or postnatal life can emerge as diseases much later in life are now being accepted as a recurring phenomenon. In this regard, inorganic arsenic is a multisite human carcinogen found at high levels in the drinking water of millions of people, although it has been difficult until recently to produce tumors in rodents with this metalloid. A mouse...

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PMID: 21071725
DOI: 10.1093/toxsci/kfq342

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