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Article

Endothelial-mesenchymal transition and its contribution to the emergence of stem cell phenotype.

Seminars in cancer biology - 1 Oct 2012

Medici Damian, Kalluri Raghu

Abstract excerpt

Vascular endothelial cells can demonstrate considerable plasticity to generate other cell types during embryonic development and disease progression. This process occurs through a cell differentiation mechanism known as endothelial-mesenchymal transition (EndMT). The generation of mesenchymal cells from endothelium is a crucial step in endothelial cell differentiation to several lineages including fibroblasts,...

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Identifiers

PMID: 22554794
DOI: 10.1016/j.semcancer.2012.04.004
PMCID: PMC3422405

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