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Article

The role of endothelial-mesenchymal transition in heterotopic ossification

2 Jul 2012

Abstract excerpt

Heterotopic ossification (HO) is a process by which bone forms in soft tissues, in response to injury, inflammation, or genetic disease. This usually occurs by initial cartilage formation, followed by endochondral ossification. A rare disease called fibrodysplasia ossificans progressiva (FOP) allows this mechanism to be induced by a combination of genetic mutation and acute inflammatory responses. FOP patients...

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PMID: 22806925
DOI: 10.1002/jbmr.1691

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