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Article

Molecular Profiling of Low-Grade Appendiceal Mucinous Neoplasms (LAMN).

Genes, chromosomes & cancer - 1 Oct 2024

Doll Julia, Maurus Katja, Köhler Franziska, Matthes Niels, Lock Johan F, Germer Christoph-Thomas, Rosenwald Andreas, Wiegering Armin

Abstract excerpt

Low-grade appendiceal mucinous neoplasia (LAMN) represents a relatively rare tumor of the appendix typically diagnosed incidentally through appendectomy for acute appendicitis. In cases where perforation occurs, mucinous content may disseminate into the abdominal cavity, leading to the development of pseudomyxoma peritonei (PMP). The primary objective of this study was to elucidate the molecular characteristics...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39400480
DOI: 10.1002/gcc.23270

Genes

KRAS
GNAS
BRAF
SMAD4
TP53

Variants

Provenance

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