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Establishing Novel Molecular Subtypes of Appendiceal Cancer.

Annals of surgical oncology - 1 Mar 2022

Garland-Kledzik Mary, Scholer Anthony, Ensenyat-Mendez Miquel, Orozco Javier I J, Khader Adam, Santamaria-Barria Juan, Fischer Trevan, Pigazzi Alessio, Marzese Diego M

Abstract excerpt

PURPOSE: Appendiceal cancer is a rare disease process with complex treatment strategies. The objective of this study was to identify mutation-based genetic subtypes that may differ from the current histological classification, compare the genetic make-up of primaries and metastases, and find novel targetable alterations. METHODS: The analyses involved the curation and normalization of gene mutation panels from...

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PMID: 34718915
DOI: 10.1245/s10434-021-10945-8

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