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Article

Molecular alterations of PI3K/Akt/mTOR pathway: a therapeutic target in endometrial cancer.

TheScientificWorldJournal - 1 Jan 2014

Pavlidou Athanasia, Vlahos Nikos F

Abstract excerpt

It is well established that the PI3K/Akt/mTOR pathway plays a central role in cell growth and proliferation. It has also been suggested that its deregulation is associated with cancer. Genetic alterations, involving components of this pathway, are often encountered in endometrial cancers. Understanding and identifying the rate-limiting steps of this pathway would be crucial for the development of novel therapies...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Phosphatidylinositol 3-Kinases

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Share to Proto-Oncogene Proteins c-akt

Share to TOR Serine-Threonine Kinases

Source

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Identifiers

PMID: 24526917
DOI: 10.1155/2014/709736
PMCID: PMC3913524

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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