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Article

Cellular energetics and mitochondrial uncoupling in canine aging.

GeroScience - 1 Apr 2019

Nicholatos Justin W, Robinette Timothy M, Tata Saurabh V P, Yordy Jennifer D, Francisco Adam B, Platov Michael, Yeh Tiffany K, Ilkayeva Olga R, Huynh Frank K, Dokukin Maxim, Volkov Dmytro, Weinstein Michael A, Boyko Adam R, Miller Richard A, Sokolov Igor, Hirschey Matthew D, Libert Sergiy

Abstract excerpt

The first domesticated companion animal, the dog, is currently represented by over 190 unique breeds. Across these numerous breeds, dogs have exceptional variation in lifespan (inversely correlated with body size), presenting an opportunity to discover longevity-determining traits. We performed a genome-wide association study on 4169 canines representing 110 breeds and identified novel candidate regulators of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30937823
DOI: 10.1007/s11357-019-00062-6
PMCID: PMC6544733

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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