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Article

Mechanisms of bacterial resistance to antimicrobial agents

15 Jun 1997

Abstract excerpt

The mechanisms behind the development and spread of bacterial resistance to antimicrobial drugs are reviewed. The chief mechanisms by which antimicrobials act are interference with nucleic acid synthesis, binding to ribosomes, and inhibition of cell-wall synthesis and folate metabolism. Bacteria have evolved genetic and biochemical ways of resisting these antimicrobial actions. Genetic mechanisms include mutation...

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Share to Antibiotic Resistance in Bacteria
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Identifiers

PMID: 9194989
DOI: 10.1093/ajhp/54.12.1420

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Source receipt: pubmed, retrieved 7 Sept 2026.

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