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Autophagy Dysfunction and its Link to Alzheimer’s Disease and Type II Diabetes Mellitus

1 Apr 2014

Abstract excerpt

Epidemiological data testifies the increasing incidence of Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM). Some associations were made between occidental lifestyle and development of these pathologies, moreover AD and T2DM are linked since each pathology is a causative risk factor for the other. Interestingly, autophagy, a catabolic pathway whose efficiency declines with age is importantly impaired...

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PMID: 24059314
DOI: 10.2174/18715273113126660146

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