Article
Frequency of CDH1 germline variants and contribution of dietary habits in early age onset gastric cancer patients in Brazil.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Sept 2019
Guindalini Rodrigo Santa Cruz, Cormedi Marina Cândido Visontai, Maistro Simone, Pasini Fátima Solange, Branas Priscila Cristina Abduch Adas, Dos Santos Liliane, de Lima Pereira Gláucia Fernanda, de Bock Geertruida Hendrika, Saccaro Daniela Marques, Katayama Maria Lucia Hirata, Faraj Sheila Friedrich, Safatle-Ribeiro Adriana, Ribeiro Junior Ulysses, Diz Maria Del Pilar Estevez, de Gouvêa Ana Carolina Ribeiro Chaves, Chammas Roger, Folgueira Maria Aparecida Azevedo Koike
Abstract excerpt
INTRODUCTION: The contribution of CDH1 germline variants to gastric cancer burden among young adults is unknown in Brazil. We aimed to evaluate the frequency of CDH1 germline variants and the diet/lifestyle habits in early age onset gastric cancer (EOGC, ≤ 55 years old) patients. METHODOLOGY: From 2013 to 2015, a total of 88 unrelated and consecutive patients diagnosed with EOGC were enrolled. All CDH1 exons and...
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