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Article

Young-Onset Gastric Cancer: Clinical and Genetic Perspectives.

Journal of gastric cancer - 1 Jan 2026

Michelon Isabella, Saeed Anwaar

Abstract excerpt

Young-onset gastric cancer (YOGC) is an increasingly recognized subtype that challenges traditional assumptions about gastric cancer (GC) biology. Although the overall global incidence of GC continues to decline, the rising burden among individuals aged <40 years has reshaped clinical perceptions, highlighting YOGC as a distinct entity with unique drivers and unmet needs. It is frequently associated with...

Topics

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Age of Onset
Early Detection of Cancer
Environmental Exposure
Incidence
Liquid Biopsy
Medical History Taking

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Staging

Stomach Neoplasms

Source

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Identifiers

PMID: 41517847
DOI: 10.5230/jgc.2026.26.e9
PMCID: PMC12802042

Genes

GC
CDH1
CLDN18
RHOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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