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Article

Effect of deletion of the rgpA gene on selected virulence of Porphyromonas gingivalis

22 Apr 2016

Abstract excerpt

The most potent virulence factors of the periodontal pathogen Porphyromonas gingivalis are gingipains, three cysteine proteases (RgpA, RgpB, and Kgp) that bind and cleave a wide range of host proteins. Considerable proof indicates that RgpA contributes to the entire virulence of the organism and increases the risk of periodontal disease by disrupting the host immune defense and destroying the host tissue....

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PMID: 30894985
DOI: 10.1016/j.jds.2016.03.004

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Effect of deletion of the rgpA gene on selected virulence of Porphyromonas gingivalisPMID 30894985Read ↗

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