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Article

Attenuation of the virulence of Porphyromonas gingivalis by using a specific synthetic Kgp protease inhibitor.

Infection and immunity - 1 Dec 2002

Curtis M A, Aduse Opoku J, Rangarajan M, Gallagher A, Sterne J A C, Reid C R, Evans H E A, Samuelsson B

Abstract excerpt

The Arg- and Lys-gingipains of Porphyromonas gingivalis are important virulence determinants in periodontal disease and may correspond to targets for immune- or drug-based treatment strategies. In this investigation we aimed to determine which of these enzymes represents the most promising molecu...

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Source

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Identifiers

PMID: 12438376
DOI: 10.1128/IAI.70.12.6968-6975.2002
PMCID: PMC132948

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12438376-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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