Role of Arg-gingipain A in virulence of Porphyromonas gingivalis.

doi:10.1128/IAI.66.3.1159-1166.1998

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Article

Role of Arg-gingipain A in virulence of Porphyromonas gingivalis.

Infection and immunity - 1 Mar 1998

Tokuda M, Karunakaran T, Duncan M, Hamada N, Kuramitsu H

Abstract excerpt

In order to access the role of the Porphyromonas gingivalis Arg-gingipain proteases in the virulence of this organism, a mutant defective in the rgpA gene was constructed in strain 381. This mutant, MT10, displayed only 40% of the Arg-specific cysteine protease activity of the wild-type strain. I...

Topics

Adhesins, Bacterial
Animals
Collagen
Cysteine Endopeptidases
Fimbriae, Bacterial
Genetic Complementation Test
Gingipain Cysteine Endopeptidases
Hemagglutinins
Mutation
Porphyromonas gingivalis
Rats
Virulence

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