Article
Role of Arg-gingipain A in virulence of Porphyromonas gingivalis.
Infection and immunity - 1 Mar 1998
Tokuda M, Karunakaran T, Duncan M, Hamada N, Kuramitsu H
Abstract excerpt
In order to access the role of the Porphyromonas gingivalis Arg-gingipain proteases in the virulence of this organism, a mutant defective in the rgpA gene was constructed in strain 381. This mutant, MT10, displayed only 40% of the Arg-specific cysteine protease activity of the wild-type strain. In addition, MT10, as well as the recently characterized protease mutant G-102, which is defective in the rgpB gene,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.