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RNAi Screening-based Identification of USP10 as a Novel Regulator of Paraptosis

20 Mar 2019

Abstract excerpt

Accumulating reports demonstrate that apoptosis does not explain all the effects of cancer therapy due to the innate and acquired apoptotic resistance of malignant cancer cells. Recently, paraptosis, a type of programmed cell death accompanied by dilation of mitochondria and/or the endoplasmic reticulum (ER), has garnered interest in cancer research as an alternative way to kill apoptosis-resistant cancers. We...

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PMID: 30894572
DOI: 10.1038/s41598-019-40982-z

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