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Article

HMGB1 as a Potential Biomarker and Therapeutic Target for Malignant Mesothelioma

12 Feb 2019

Abstract excerpt

Malignant mesothelioma (MM) is a rare, aggressive, and highly lethal cancer that is substantially induced by exposure to asbestos fibers. High-mobility group box 1 (HMGB1) is an intriguing proinflammatory molecule involved in MM. In this review, we describe the possible crucial roles of HMGB1 in carcinogenic mechanisms based on in vivo and in vitro experimental evidence and outline the clinical findings of...

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Identifiers

PMID: 30891101
DOI: 10.1155/2019/4183157

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