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Article

Genetic interpretation and clinical translation of minor genes related to Brugada syndrome

1 Mar 2019

Abstract excerpt

Brugada syndrome (BrS) is an inherited arrhythmogenic disease associated with sudden cardiac death. The main gene is SCN5A. Additional variants in 42 other genes have been reported as deleterious, although these variants have not yet received comprehensive pathogenic analysis. Our aim was to clarify the role of all currently reported variants in minor genes associated with BrS. We performed a comprehensive...

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PMID: 30821013
DOI: 10.1002/humu.23730

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