Article
SCN5A mutation status increases the risk of major arrhythmic events in Asian populations with Brugada syndrome: systematic review and meta-analysis.
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc - 1 Jan 2019
Rattanawong Pattara, Chenbhanich Jirat, Mekraksakit Poemlarp, Vutthikraivit Wasawat, Chongsathidkiet Pakawat, Limpruttidham Nath, Prasitlumkum Narut, Chung Eugene H
Abstract excerpt
BACKGROUND: Brugada syndrome (BrS) is an inherited arrhythmic disease linked to SCN5A mutations. It is controversial whether SCN5A mutation carriers possess a greater risk of major arrhythmic events (MAE). We examined the association of SCN5A mutations and MAE in BrS patients. METHODS: We comprehensively searched the databases of MEDLINE and EMBASE from inception to September 2017. Included studies were published...
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