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Article

Clinical Features of Brugada Syndrome Patients With SCN5A Variants.

Journal of cardiovascular electrophysiology - 1 Jun 2025

Okamura Sho, Ochi Hidenori, Nakashima Mika, Akiyama Rie, Tokuyama Takehito, Okubo Yousaku, Miyauchi Shunsuke, Miyamoto Shogo, Oguri Naoto, Uotani Yukimi, Sakai Takumi, Furutani Motoki, Kihara Yasuki, Nakano Yukiko

Abstract excerpt

BACKGROUND: SCN5A is the most common susceptibility gene in patients with Brugada syndrome (BrS); however, the interpretation and management of benign or variants of unknown clinical significance (VUS) in SCN5A remains a challenge despite the availability of genetic testing. OBJECTIVE: This study aimed to investigate the relationship between the SCN5A variants and clinical symptoms of BrS patients. METHODS: We...

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Identifiers

PMID: 40125570
DOI: 10.1111/jce.16643
PMCID: PMC12160668

Genes

SCN5A

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