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Merkel Cell Polyomavirus Infection and Detection

7 Feb 2019

Abstract excerpt

Merkel cell polyomavirus (MCPyV) infection can lead to Merkel cell carcinoma (MCC), a highly aggressive form of skin cancer. Mechanistic studies to fully investigate MCPyV molecular biology and oncogenic mechanisms have been hampered by a lack of adequate cell culture models. Here, we describe a set of protocols for performing and detecting MCPyV infection of primary human skin cells. The protocols describe the...

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PMID: 30799855
DOI: 10.3791/58950

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