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Article

Dynamic alterations of plasma cell free DNA in response to chemotherapy in children with neuroblastoma

21 Feb 2019

Abstract excerpt

BACKGROUND: To improve cure rates for neuroblastoma (NB), it is important and necessary to evaluate therapy response. Our investigation focuses on using plasma cell free DNA (cfDNA) as a biomarker to determine tumor burden and minimal residual disease (MRD) of NB patients during chemotherapy. METHODS: Total 58 NB patients were recruited from July 2016 to December 2017. Therapy regime and risk classification were...

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PMID: 30793512
DOI: 10.1002/cam4.2045

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