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Whole exome sequencing reveals novel somatic alterations in neuroblastoma patients with chemotherapy

17 Feb 2018

Abstract excerpt

BACKGROUND: We ought to explore the acquired somatic alterations, shedding light on genetic basis of somatic alterations in NB patients with chemotherapy. METHODS: Marrow blood samples from NB patients were collected before treatment, after the 2nd and 4th chemotherapy for baseline research and continuous monitoring by whole exome sequencing. Plasma cell free DNA (cfDNA) was prepared for baseline research. Finger...

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PMID: 29467591
DOI: 10.1186/s12935-018-0521-3

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