Article
An induced mutation of ABC-transporter component VraF(K84E) contributes to vancomycin resistance and virulence in Staphylococcus aureus strain MW2.
International journal of medical microbiology : IJMM - 1 Jun 2024
Cao Ruobing, Su Huimin, Wei Zichun, He Zhien, Pan Ting, Li Yujie, Sun Baolin
Abstract excerpt
Staphylococcus aureus is a notorious pathogen responsible for various severe diseases. Due to the emergence of drug-resistant strains, the prevention and treatment of S. aureus infections have become increasingly challenging. Vancomycin is considered to be one of the last-resort drugs for treating most methicillin-resistant S. aureus (MRSA), so it is of great significance to further reveal the mechanism of...
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