VraH Is the Third Component of the Staphylococcus aureus VraDEH System Involved in Gallidermin and Daptomycin Resistance and Pathogenicity

Abstract excerpt

In bacteria, extracellular signals are transduced into the cell predominantly by two-component systems (TCSs) comprising a regulatory unit triggered by a specific signal. Some of the TCSs control executing units such as ABC transporters involved in antibiotic resistance. For instance, inStaphylococcus aureus, activation of BraSR leads to the upregulation ofvraDEexpression that encodes an ABC transporter playing a...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antimicrobial Resistance in Staphylococcus
• Share to Bacterial Genetics and Biotechnology
• Share to RNA and protein synthesis mechanisms