Article
Janus kinase 1/2 inhibition with baricitinib in the treatment of juvenile dermatomyositis
4 Jan 2019
Abstract excerpt
Sir, We read with interest the recent article by Ladislau and colleagues reporting on the pathogenicity of type I interferon (IFN) in vitro and evaluating the efficacy of type I interferon pathway blockade for therapeutic purposes in adults with dermatomyositis (Ladislau et al., 2018). The authors demonstrated that activation of type I IFN in differentiating myoblasts abolished myotube formation with reduced...
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