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Therapeutic antisense oligonucleotides for movement disorders

13 Jul 2020

Abstract excerpt

Movement disorders are a group of neurological conditions characterized by abnormalities of movement and posture. They are broadly divided into akinetic and hyperkinetic syndromes. Until now, no effective symptomatic or disease-modifying therapies have been available. However, since many of these disorders are monogenic or have some well-defined genetic component, they represent strong candidates for antisense...

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PMID: 32656818
DOI: 10.1002/med.21706

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