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Article

Prolonged febrile seizures induce inheritable memory deficits in rats through DNA methylation

21 Jan 2019

Abstract excerpt

AIMS: Febrile seizures (FSs) are the most common types of seizures in young children. However, little is known whether the memory deficits induced by early-life FSs could transmit across generations or not. METHODS: The memory functions of different generations of FS rats were behaviorally evaluated by morris water maze, inhibitory avoidance task, and contextual fear conditioning task. Meanwhile, molecular...

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Share to Epigenetics and DNA Methylation
Share to Epilepsy research and treatment
Share to Neurogenesis and neuroplasticity mechanisms

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PMID: 30666786
DOI: 10.1111/cns.13088

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