Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GMP-compatible and xeno-free cultivation of mesenchymal progenitors derived from human-induced pluripotent stem cells

11 Jan 2019

Abstract excerpt

BACKGROUND: Human mesenchymal stem cells are a strong candidate for cell therapies owing to their regenerative potential, paracrine regulatory effects, and immunomodulatory activity. Yet, their scarcity, limited expansion potential, and age-associated functional decline restrict the ability to consistently manufacture large numbers of safe and therapeutically effective mesenchymal stem cells for routine clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Ethics and Regulation
Share to Mesenchymal stem cell research
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30635059
DOI: 10.1186/s13287-018-1119-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GMP-compatible and xeno-free cultivation of mesenchymal progenitors derived from human-induced pluripotent stem cellsPMID 30635059Read ↗

Generation of clinical-grade human induced pluripotent stem cells in Xeno-free conditionsSemantic proximity Read ↗

Development and evaluation of a novel xeno-free culture medium for human-induced pluripotent stem cellsSemantic proximity Read ↗

Quality assessment of a serum and xenofree medium for the expansion of human GMP-grade mesenchymal stromal cells.Semantic proximity Read ↗

Application of mesenchymal stem cells derived from human pluripotent stem cells in regenerative medicineSemantic proximity Read ↗

Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissuesSemantic proximity Read ↗

Development and characterization of a clinically compliant xeno-free culture medium in good manufacturing practice for human multipotent mesenchymal stem cells.Semantic proximity Read ↗

Production of Mesenchymal Stem Cells through Stem Cell ReprogrammingSemantic proximity Read ↗

Advancements and Innovative Strategies in Induced Pluripotent Stem Cell‐Derived Mesenchymal Stem Cell Therapy: A Comprehensive ReviewSemantic proximity Read ↗

A therapy-grade protocol for differentiation of pluripotent stem cells into mesenchymal stem cells using platelet lysate as supplement.Semantic proximity Read ↗

Human mesenchymal stem cells maintain their phenotype, multipotentiality, and genetic stability when cultured using a defined xeno-free human plasma fraction.Semantic proximity Read ↗

Current Applications of Human Pluripotent Stem Cells: Possibilities and ChallengesSemantic proximity Read ↗

Production of Human Pluripotent Stem Cell Therapeutics under Defined Xeno-free Conditions: Progress and ChallengesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.