Article
A therapy-grade protocol for differentiation of pluripotent stem cells into mesenchymal stem cells using platelet lysate as supplement.
Stem cell research & therapy - 12 Jan 2015
Luzzani Carlos, Neiman Gabriel, Garate Ximena, Questa María, Solari Claudia, Fernandez Espinosa Darío, García Marcela, Errecalde Ana Lía, Guberman Alejandra, Scassa María Elida, Sevlever Gustavo Emilio, Romorini Leonardo, Miriuka Santiago Gabriel
Abstract excerpt
INTRODUCTION: Mesenchymal stem cells (MSCs) are a promising source of cells for regenerative therapies. Although they can be isolated easily from several tissues, cell expansion is limited since their properties are lost with successive passages. Hence, pluripotent derived MSCs (PD-MSCs) arise as a suitable alternative for MSC production. Nevertheless, at present, PD-MSC derivation protocols are either expensive...
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