Article
Quality assessment of a serum and xenofree medium for the expansion of human GMP-grade mesenchymal stromal cells.
PeerJ - 1 Jan 2022
Aussel Clotilde, Busson Elodie, Vantomme Helene, Peltzer Juliette, Martinaud Christophe
Abstract excerpt
Background: Cell-based therapies are emerging as a viable modality to treat challenging diseases, resulting in an increasing demand for their large-scale, high-quality production. Production facilities face the issue of batch-to-batch consistency while producing a safe and efficient cell-based product. Controlling culture conditions and particularly media composition is a key factor of success in this challenge....
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